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American Journal of Lifestyle Medicine, Vol. 1, No. 1, 24-28 (2007)
DOI: 10.1177/1559827606294793

Reviews

Dietary Factors in Reducing Risk of Cardiovascular Diseases

Kathleen J. Melanson, PhD, RD, LD

Department of Nutrition and Food Sciences, University of Rhode Island, Kingston, kmelanson{at}uri.edu

Diet influences many modifiable risk factors for cardiovascular diseases (CVDs). Considering this, moderation of total dietary fat, particularly trans and saturated fats, as well as cholesterol is recommended. Dietary fats should come mainly from plants and fatty fish, providing monounsaturated and polyunsaturated (including omega-3) fatty acids. Carbohydrate sources to emphasize include whole grains, legumes, vegetables, fruits, and other fiber-rich sources, rather than sugars. Although vitamins such as E, C, and some B vitamins are associated with reduced CVD risk, data do not support the use of supplements, but foods rich in these nutrients are advocated. Dietary minerals such as potassium, magnesium, and calcium may be beneficial to heart health, while reduction of dietary sodium decreases risk of hypertension. A large variety of phytonutrients are also associated with reduced CVD risk. Other dietary factors receiving research attention regarding CVD risk. Other dietary factors receiving research attention regarding CVD risk include caffeine, alcobol, and meal frequency, although more work is needed in these areas. In contrast, data are quite robust to support the importance of healthy body weight management in cardiovascular health. In general, diets based on a variety of less processed foods, mainly of plant origin, in the context of an active lifestyle, are conducive to heart health.

Key Words: heart disease • coronary artery disease • metabolic syndrome • nutrition • foods

References

  • DeCaterina RD, Zampolli A, Del Turco S, Madonna R, Massaro M. Nutritional mechanisms that influence cardiovascular disease. Am J Clin Nutr. 2006-83(suppl): 421S-426S.[Abstract/Free Full Text]
  • World Health Organization. Global Strategy on diet physical activity and health. Fifty-seventh World Health Assembly WHA57.17 Agenda Item 12.6; 2004.
  • Krauss RM, Eckel RH, Howard B, et al. AHA dietary guidelines: revision 2000: a statement for healthcare professionals from the nutrition committee of the American Heart Association. Circulation. 2000; 102: 2284-2299.
  • Hu FB, Manson JE, Willett WC. Types of dietary fat and risk of coronary heart disease: a critical review. J Am Coll Nutr. 2001;20: 5-19.[Abstract/Free Full Text]
  • Schaefer EJ. Lipoproteins, nutrition, and heart disease. Am J Clin Nutr. 2002;75: 191-212.[Abstract/Free Full Text]
  • Sacks FM, Katan M. Randomized clinical trials on the effects of dietary fat and carbohydrate on plasma lipoproteins and cardiovascular disease. Am J Med. 2002;113(9B): 13S-24S.
  • Suh I, Oh KW, Lee KH, et al. Moderate dietary fat consumption as a risk factor for ischemic heart disease in a population with a low fat intake: a case-control study in Korean men. Am J Clin Nutr. 2001;73: 722-727.[Abstract/Free Full Text]
  • Griffin B, Lee A. Dietary cholesterol, eggs and coronary heart disease risk in perspective. Nutr Bull. 2006;31: 21-21.[CrossRef]
  • Fernandez ML. Dietary cholesterol provided by eggs and plasma lipoproteins in healthy populations. Curr Opin Clin Nutr Metab Care. 2006;9: 8-12.[Medline] [Order article via Infotrieve]
  • Weggemans RM, Zock PL, Katan MB. Dietary cholesterol from eggs increases the ratio of total cholesterol to high-density lipoprotein cholesterol in humans: a meta-analysis. Am J Clin Nutr. 2002;75: 333-335.[Free Full Text]
  • Egg consumption, serum cholesterol, and cause-specific and all-cause mortality: the National Integrated Project for Prospective Observation of Non-communicable Disease and Its Trends in the Aged, 1980 (NIPPON DATA80). Am J Clin Nutr 2004;80: 58-63.[Abstract/Free Full Text]
  • Leeds AR. Glycemic index and heart disease. Am J Clin Nutr. 2002;76(suppl): 286S-289S.[Abstract/Free Full Text]
  • McKeown NM, Meigs JB, Liu S, Saltzman E, Wilson PW, Jaques PF. Carbohydrate nutrition, insulin resistance, and the prevalence of the metabolic syndrome in the Framingham Offspring Cohort. Diabetes Care. 2004;27: 538-546.[Abstract/Free Full Text]
  • Truswell AS. Cereal grains and coronary heart disease. Eur J Clin Nutr. 2002;56: 1-14.[CrossRef][Medline] [Order article via Infotrieve]
  • Slavin J. Why whole grains are protective: biological mechanisms. Proc Nutr Soc. 2003;62: 129-134.[CrossRef][Medline] [Order article via Infotrieve]
  • Ludwig DS, Pereira MA, Kroenke CH, et al. Dietary fiber, weight gain, and cardiovascular disease risk factors in young adults. JAMA. 1999;282: 1539-1546.[Abstract/Free Full Text]
  • Davy BM, Melby CL. The effect of fiber-rich carbohydrates on features of Syndrome X. J Am Diet Assoc. 2003;103: 86-96.[CrossRef][Medline] [Order article via Infotrieve]
  • Ballesteros MN, Cabrera RM, Saucedo MS, Yepiz-Plascencia GM, Ortega MI, Valencia ME. Dietary fiber and lifestyle influence serum lipids in free living adult men. J Am Coll Nutr. 2001;20: 649-655.[Abstract/Free Full Text]
  • Lairon D, Arnault N, Bertrais S, et al. Dietary fiber intake and risk factors for cardiovascular disease in French adults. Am J Clin Nutr. 2005;82: 1185-1194.[Abstract/Free Full Text]
  • Brown L, Rosner B, Willett WW, Sacks FM. Cholesterol-lowering effects of dietary fiber: a meta-analysis. Am J Clin Nutr. 1999;69: 30-42.[Abstract/Free Full Text]
  • Daly M. Sugars, insulin sensitivity, and the postprandial state. Am J Clin Nutr. 2003;78(suppl): 865S-872S.[Abstract/Free Full Text]
  • Fried SK, Rao SP. Sugars, hypertriglyceridemia, and cardiovascular disease. Am J Clin Nutr. 2003;78(suppl): 873S-880S.[Abstract/Free Full Text]
  • Chattopadhyaya A, Bandyopadhyay D. Vitamin E in the prevention of ischemic heart disease. Pharmacol Rep 2006;58: 179-187.[Medline] [Order article via Infotrieve]
  • Lee IM, Cook NR, Gaziano JM, et al. Vitamin E in the primary prevention of cardiovascular disease and cancer: the Women's Health Study: a randomized control trial. JAMA. 2005;294: 56-65.[Abstract/Free Full Text]
  • Sanchez-Moreno C, Dashe JF, Scott T, Thaler D, Folstein MF, Martin A. Decreased levels of plasma vitamin C and increased concentrations of inflammatory and oxidative stress markers after stroke. Stroke. 2004;35: 163-168.[Abstract/Free Full Text]
  • Nam CM, Oh KW, Lee KH, et al. Vitamin C intake and risk of ischemic heart disease in a population with a high prevalence of smoking. J Am Coll Nutr. 2003;22: 372-378.[Abstract/Free Full Text]
  • Harats D, Chevion S, Nahir M, Norman Y, Sagee O, Berry EM. Citrus fruit supplementation reduces lipoprotein oxidation in young men ingesting a diet high in saturated fat: presumptive evidence for an interaction between vitamins C and E in vivo. Am J Clin Nutr. 1998;67: 240-245.[Abstract]
  • Naidu KA. Vitamin C in human health and disease is still a mystery? An overview. Nutr J. 2003;2: 7-7.[CrossRef][Medline] [Order article via Infotrieve]
  • Woodside JV, Young IS, Yarnell JW, et al. Antioxidants, but not B-group vitamins increase the resistance of low-density lipo-protein to oxidation: a randomized factorial design, placebo-controlled trial. Atherosclerosis. 1999;144: 419-427.[CrossRef][Medline] [Order article via Infotrieve]
  • Siri PW, Verhoef P, Kok FJ. Vitamins B6, B12, and folate: association with plasma total homocysteine and risk of coronary atherosclerosis. J Am Coll Nutr. 1998;17: 435-441.[Abstract/Free Full Text]
  • Robinson K, Arheart K, Refsum H, et al. Low circulating folate and vitamin B6 concentrations: risk factors for stroke, peripheral vascular disease, and coronary artery disease. European COMPAC Group. Circulation. 1998;97: 437-443.
  • Forman JP, Rimm EB, Stampfer MJ, Curhan GC. Folate intake and the risk of incident hypertension among US women. JAMA. 2005;293: 320-329.[Abstract/Free Full Text]
  • Loria CM, Ingram DD, Feldman JJ, Wright JD, Madans JH. Serum folate and cardiovascular disease mortality among US men and women. Arch Intern Med. 2000;160: 3258-3262.[Abstract/Free Full Text]
  • Rampersaud GC, Kauwell GP, Bailey LB. Folate: a key to optimizing health and reducing disease risk in the elderly. J Am Coll Nutr. 2003;22: 1-8.[Abstract/Free Full Text]
  • Kim MK, Ordovas JM, Selhub J, Campos H. B vitamins and plasma homocysteine concentrations in an urban and rural area of Costa Rica. J Am Coll Nutr. 2003;22: 224-231.[Abstract/Free Full Text]
  • Tucker KL, Olson B, Bakun P, Dallal GE, Selhub J, Rosenberg IH. Breakfast cereal fortified with folic acid, vitamin B-6, and vitamin B-12 increases vitamin concentrations and reduces homocysteine concentrations: a randomized trial. Am J Clin Nutr. 2004;79: 805-811.[Abstract/Free Full Text]
  • He K, Merchant K, Rimm EB, et al. Folate, vitamin B6, and B12 intakes in relation to risk of stroke among men. Stroke. 2004;35: 169-174.[Abstract/Free Full Text]
  • Friso S, Girelli D, Martinelli N, et al. Low plasma vitamin B-6 concentrations and modulation of coronary artery disease risk. Am J Clin Nutr. 2004;79: 992-998.[Abstract/Free Full Text]
  • He FJ, MacGregor GA. Effect of longer-term modest salt reduction on blood pressure. Cochrane Database Syst Rev. 2004;(3): CD004937-CD004937.
  • Sacks FM, Svetkey LP, Vollmer WM, et al. Effects on blood pressure of reduced dietary sodium and the Dietary Approaches to Stop Hypertension (DASH) diet. N Engl J Med. 2001;344: 3-10.[Abstract/Free Full Text]
  • Khaw KT, Bingham S, Welsh A, et al. Blood pressure and urinary sodium in men and women: the Norfolk Cohort of the European Prospective Investigation into Cancer (EPIC-Norfolk). Am J Clin Nutr. 2004;80: 1397-1403.[Abstract/Free Full Text]
  • Al-Delaimy WK, Rimm EB, Willet WC, Stampfer MJ, Hu FB. Magnesium intake and risk of coronary heart disease among men. J Am Coll Nutr. 2004;23: 63-70.[Abstract/Free Full Text]
  • Vaskonen T. Dietary minerals and modification of cardiovascular risk factors. J Nutr Biochem. 2003;14: 492-506.[CrossRef][Medline] [Order article via Infotrieve]
  • Rosolova H, Mayer O Jr, Reaven G. Effect of variations in plasma magnesium concentration on resistance to insulin-mediated glucose disposal in nondiabetic subjects. J Clin Endocrinol Metab. 1997;82: 3783-3785.[Abstract/Free Full Text]
  • Tam M, Gomez S, Gonzalez-Gross M, Marcos A. Possible roles of magnesium on the immune system. Eur J Clin Nutr. 2003;57: 1193-1197.[CrossRef][Medline] [Order article via Infotrieve]
  • Zemel MB. Calcium modulation of hyper-tension and obesity: mechanisms and implications. J Am Coll Nutr. 2001;20(5 suppl): 428S-435S.[Abstract/Free Full Text]
  • Bostick RM, Kushi LH, Wu Y, Meyer KA, Sellers TA, Folsam AR. Relation of calcium, vitamin D, and dairy food intake to ischemic heart disease mortality among post-menopausal women. Am J Epidemiol. 1999;149: 151-161.[Abstract/Free Full Text]
  • Kris-Etherton PM, Hecker KD, Bonanome A, et al. Bioactive compounds in foods: their role in the prevention of cardiovascular disease and cancer. Am J Med. 2002;113(suppl 9B): 71S-88S.
  • Hasler CM. Functional foods: benefits, concerns, and challenges—a position paper from the American Council on Science and Health. J Nutr. 2002;132: 3772-3781.[Abstract/Free Full Text]
  • ADA reports: position of the American Dietetic Association: functional foods. J Am Diet Assoc. 2004;104: 814-826.[CrossRef][Medline] [Order article via Infotrieve]
  • Happonen P, Voutilanen S, Salonen JT. Coffee drinking is dose-dependently related to risk of acute coronary events in middle-aged men. J Nutr. 2004;134: 2381-2386.[Abstract/Free Full Text]
  • Jenkins DJ, Wolever TM, Vuksan V, et al. Nibbling versus gorging: metabolic advantages of increased meal frequency. N Engl J Med 1989;321: 929-934.[Abstract]
  • Arnold LM, Ball MJ, Duncan AW, Mann J. Effect of isoenergetic intake of three or nine meals on plasma lipoproteins and glucose metabolism. Am J Clin Nutr. 1993;57: 446-451.[Abstract/Free Full Text]
  • Edelstein SL, Barrett-Connor EL, Wingard DL, Cohn BA. Increased meal frequency associated with decreased cholesterol concentrations; Rancho Bernardo, CA, 1984-1987. Am J Clin Nutr. 1992;55: 664-669.[Abstract/Free Full Text]
  • Stanton JJ, Keast D. Serum cholesterol, fat intake, and breakfast consumption in the United States adult population. J Am Coll Nutr. 1989;8: 567-572.[Abstract]
  • Farshchi HR, Taylor MA, Macdonald IA. Deleterious effects of omitting breakfast on insulin sensitivity and fasting lipid profiles in healthy lean women. Am J Clin Nutr. 2005;81: 388-396.[Abstract/Free Full Text]
  • Farshchi HR, Taylor MA, Macdonald IA. Beneficial effects of regular meal frequency on thermogenesis, insulin sensitivity and fasting lipid profiles in healthy obese women. Am J Clin Nutr. 2005;81: 16-24.[Abstract/Free Full Text]
  • National Institutes of Health. Clinical Guidelines on the Identification, Evaluation, and Treatment of Overweight and Obesity in Adults—The Evidence Report. Bethesda, Md: National Heart, Lung and Blood Institute; 1998.
  • Sjöström CD, Lissner L, Sjöström L. Relationships between changes in body composition and changes in cardiovascular risk factors: the SOS Intervention Study. Swedish Obese Subjects. Obes Res. 1998;5: 519-530.
  • Wadden TA, Anderson DA, Foster GD. Two-year changes in lipids and lipoproteins associated with the maintenance of a 5% to 10% reduction in initial weight: some findings and some questions. Obes Res 1999;7: 170-178.[Medline] [Order article via Infotrieve]

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