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Lifestyle and Risk of Cardiovascular Disease and Type 2 Diabetes in Women: A Review of the Epidemiologic Evidence

Division of Preventive Medicine, Brigham and Women's Hospital, Boston, Massachusetts, sbassuk{at}rics.bwh.harvard.edu

JoAnn E. Manson, MD, DrPH

Division of Preventive Medicine, Brigham and Women's Hospital, Boston, Massachusetts, Harvard Medical School, Boston, Massachusetts

Cardiovascular disease is the leading cause of death among both women and men in the United States, accounting for nearly half of all deaths and considerable morbidity. Type 2 diabetes is a major risk factor for cardiovascular disease and one that is particularly potent in women; its prevalence has increased dramatically in recent years. Epidemiologic data indicate that cardiovascular disease and type 2 diabetes share common risk factors and are largely preventable; indeed, findings from the Nurses' Health Study suggest that 74% of cardiovascular disease cases, 82% of coronary heart disease cases, and 91% of diabetes cases in women could be prevented by not smoking, engaging in regular physical activity, maintaining a healthy weight, eating healthier food, and drinking moderate amounts of alcohol. This article reviews lifestyle risk factors and preventive strategies for cardiovascular disease and type 2 diabetes among women.

Key Words: cardiovascular disease • coronary heart disease • dietary factors • obesity • physical activity • smoking • stroke • type 2 diabetes

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