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American Journal of Lifestyle Medicine
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Risk Communication During Screening for Genomic Breast Cancer Susceptibility

Robert E. Gramling, MD

Brown University Center for Primary Care and Prevention, Pawtucket, Rhode Island, robert_gramling{at}brown.edu

Jennifer Irvin Vidrine, PhD

University of Texas M. D. Anderson Cancer Center, Houston

Screening for genomic predisposition to diseases of adulthood is emerging in standard medical practice. Breast cancer predisposition testing provides a useful example for understanding the potential implications of risk-related screening in practice. Risk is an important and complex psychological construct that is understood differently both between scientific disciplines and between medical and lay persons. The process of establishing thresholds for classifying whether one's risk reaches levels warranting departure from standard preventive strategies is an important predictor of both physician feedback and patient interpretation of their risk. Messages about genomic breast cancer risk arising during the pedigree screening context are conveyed via explicit and implicit modes of communication. Best practices for communicating about genomic risk and the implications for health disparities related to screening for genomic susceptibility remain unknown. More work is urgently needed given the societal forces that are catalyzing population-based screening for genomic predisposition into the routine practice of preventive medicine.

Key Words: screening • genetics • risk communication • breast cancer • primary care

American Journal of Lifestyle Medicine, Vol. 1, No. 1, 54-58 (2007)
DOI: 10.1177/1559827606295453
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